Rubén Artero Selected Research

Myotonic Dystrophy (Dystrophia Myotonica)

12/2023	Peptide-conjugated antimiRs improve myotonic dystrophy type 1 phenotypes by promoting endogenous MBNL1 expression.
6/2023	Natural Compound Boldine Lessens Myotonic Dystrophy Type 1 Phenotypes in DM1 Drosophila Models, Patient-Derived Cell Lines, and HSALR Mice.
3/2022	Proof of concept of peptide-linked blockmiR-induced MBNL functional rescue in myotonic dystrophy type 1 mouse model.
1/2022	Rapid Determination of MBNL1 Protein Levels by Quantitative Dot Blot for the Evaluation of Antisense Oligonucleotides in Myotonic Dystrophy Myoblasts.
9/2020	Therapeutic Potential of AntagomiR-23b for Treating Myotonic Dystrophy.
1/2020	Protective effects of mirtazapine in mice lacking the Mbnl2 gene in forebrain glutamatergic neurons: Relevance for myotonic dystrophy 1.
11/2019	MicroRNA-Based Therapeutic Perspectives in Myotonic Dystrophy.
1/2017	In silico discovery of substituted pyrido[2,3-d]pyrimidines and pentamidine-like compounds with biological activity in myotonic dystrophy models.
1/2017	Expanded CCUG repeat RNA expression in Drosophila heart and muscle trigger Myotonic Dystrophy type 1-like phenotypes and activate autophagocytosis genes.

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Rubén Artero Research Topics

Disease

9	Myotonic Dystrophy (Dystrophia Myotonica) 12/2023 - 01/2017
3	Myotonia 03/2023 - 09/2020
2	Muscle Weakness 03/2023 - 12/2021
1	Neuromuscular Diseases (Neuromuscular Disease) 12/2023
1	Atrophy 12/2021
1	Inborn Genetic Diseases (Disease, Hereditary) 09/2020

Drug/Important Bio-Agent (IBA)

5	Proteins (Proteins, Gene)FDA Link 03/2023 - 01/2017
2	Peptides (Polypeptides)IBA 12/2023 - 03/2022
2	RNA (Ribonucleic Acid)IBA 12/2023 - 01/2017
2	Protein Kinases (Protein Kinase)IBA 09/2020 - 01/2017
1	boldineIBA 06/2023
1	Antisense OligonucleotidesIBA 01/2022
1	Mirtazapine (Rexer)FDA LinkGeneric 01/2020
1	MicroRNAs (MicroRNA)IBA 11/2019
1	RNA Precursors (Precursor, mRNA)IBA 01/2017
1	PyrimidinesIBA 01/2017
1	Pentamidine (NebuPent)FDA LinkGeneric 01/2017